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- Abstract 文献概要
- 1ページ目 Look Inside
はじめに
1953年Grabar & Williamsが免疫電気泳動法を創始して以来,皮膚科領域でも広く応用され,数種の皮膚疾患で特有の変化が認められている。今回著者らも各種皮膚疾患に対して本法を実施し,疾患特有の変化がみられるか否かを検討したのでその結果を報告する。
1) The serum protein was analysed with the cellulose acetate membrane immunoelectrophoresis in 25 healthy subjects. In our experiment 16 precipitation lines were almost constantly detected. The variations of the behavior of each precipitation band were observed and they were regarded as physiological. 2) In 163 patients with various skin diseases the serum was analysed with the same method. The statistically significant finding was an increase of intensity of α2-macro-globulin in syphilis, especially tertiary one, and viral dermatoses. Compared with the allergic dermatoses, the nonallergic ones showed a significantly higher increase of α2-macroglobulin. Although a statistical test was not performed because of a small number of cases, increases of α2-lipoprotein and IgM in xanthoma, marked decreases of IgG, IgA and IgM in progressive vaccinia and an increase of α2-macroglobulin in ichthyosis were thought to be the characteristic findings of respective dermatoses.

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