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Three cases of syphilitic uveitis with various findings including ASPPC and iris granuloma Masayuki Yamada 1 , Mariko Egawa 1 , Takafumi Misaki 1 , Yoshinori Mitamura 1 1Department of Ophthalmology, Institute of Biomedical Sciences, Tokushima University Graduate School pp.975-982
Published Date 2024/8/15
DOI https://doi.org/10.11477/mf.1410215248

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Abstract Purpose:To report three cases of syphilitic uveitis with acute syphilitic posterior placoid chorioretinitis(ASPPC)or rare iris granuloma.

Case 1:A 55-year-old HIV-positive male presented with a chief complaint of decreased vision and eye pain in the left eye. The best corrected visual acuity was 0.6 in the right eye and 0.3 in the left eye. An iris granuloma was found in the left eye, and marked retinal vasculitis and ASPPC in both eyes. Oral penicillin was administered, and his visual acuity improved to 1.0 in right eye and 1.2 in the left eye. The ocular inflammation subsided.

Case 2:The patient was a 41-year-old male. His chief complaints were decreased visual acuity and conjunctival hyperemia in the both eyes. The best corrected visual acuity was 1.5 in the right eye and 1.0 in the left. Both eyes showed granulomatous iritis and mild retinal vasculitis. One week later, acute macular neuroretinopathy-like findings were observed in his left eye. After intramuscular injection of a long-acting penicillin preparation, the ocular inflammation improved. The final visual acuity was 1.5 in the both eye.

Case 3:The patient was a 60-year-old male. His chief complaint was blurred vision in the left eye. The best corrected visual acuity was 0.2 in the left eye and ASPPC was observed. Oral penicillin was administered. After treatment, the outer retinal layer damage improved and the final visual acuity recovered to 1.0.

Conclusion:Although syphilitic uveitis shows various findings, the visual prognosis is good after treatment. To start treatment early, early diagnosis based on systemic examinations and the patient's background in cooperation with internal medicine is important.


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