糖尿病性網膜症無血管野の網膜感度

Sensitivity of non-perfused retinal area in diabetic retinopathy

（1）糖尿病性網膜症18眼において，螢光眼底造影検査で確認された後極部30度内の無血管野の網膜感度をオクトパス自動視野計31,32.F2プログラムを用いて検討した．

（2）無血管野は黄斑5度以内には非常に少なく，5度から15度，15度から30度耳側，同鼻側の順に多く認められた．

（3）15度以内では網膜感度低下と無血管野占有率との相関は低い．15度から30度耳側部では，網膜感度低下は無血管野占有率と良く相関したが，鼻側部では無血管野が多いにもかかわらずその感度低下は小さい．

（4）無血管野の網膜感度は種々の程度の低下が認められ，正常網膜との境界において比較的急峻に低下した．

We evaluated the retinal sensitivity in 18 eyes with diabetic retinopathy using an automated perimeter (Octopus). All the eyes manifested capil-lary non-perfused areas when seen by fluorescein angiography. The type of retinopathy was classified as simple in 2 eyes, preproliferative in 12, and proliferative in 4. The visual acuity was 0.6 in 2 eyes and 1.0 in the other 16 eyes.

We divided the posterior fundus into four regions : central area within 5° from the fovea, ring-shaped area between 5° and 15° from the fovea (area II), and an outer zone between 15° and 30° from the fovea (area III). Area III was further divided into temporal and nasal halves (area III temporal and nasal). On the fluorescein angiogram, the extent ofcapillary non-perfusion was minimal in central area and increased in area II, area III temporal and III nasal in the ascending order.

We used program 31 and 32 in evaluating the retinal sensitivity. Decrease in retinal sensitivity was not correlated with the extent of capillary non-perfusion in the retinal area within 15ｰ from the fovea. The correlation between decrease in retinal sensitivity and capillary non-perfusion was good in area III temporal and was fair in area III nasal. While the degree of impaired retinal sensitivity was variable, a relatively steep depression was present along the border between perfused and non-per-fused retinal area.

Rinsho Ganka (Jpn J Clin Ophthalmol) 41(8) : 1049-1052, 1987