Discussion to Dr. Walker's Speech

　I feel greatly honored to mention that I　have been interested in research of epileptic　convulsion and it is a particular pleasure to　be able to discuss the subjects of Dr．　Walker, since it is his provocative and　fruitful lines of research that have long in—spired most of our own investigative efforts　in the field．　I should first like to com—pliment the excellent work he just men—tioned, based on well organized instrument—ation and precise analysis of accumulated　data with modernized IBM．

　While discussing the pathways of epileptic　discharge, he pointed out an important　concept of its operational mechanism, in　addition to the one of the structural lines　of communication．　I should like to agree　with such a comment or interpretation．　The propagation of excitement is considered　in two meanings；　the one is a simple trans—mission of impulses from one structure to　other, and the other is to build up a self—sustained discharge at other structures．　I　believe that such a concept has played a　very important role to physiological approach　to the central nervous system．