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Two Cases of Generalized Tetanus Presenting with Dysphagia as an Initial Symptom Masato Kanazawa 1,4 , Hideaki Ishiguro 2 , Osamu Onodera 3 , Kenjiro Yoshikawa 2 , Takashi Koide 2 , Aki Arai 1 , Arika Hasegawa 1 , Ryouichi Nakano 1 , Keiko Tanaka 1 , Masatoyo Nishizawa 1 1Department of Neurology, Brain Reseach Institute, Niigata University 2Department of Neurology, Akita Red Cross Hospital 3Department of Molecular Neuroscience, Brain Research Institute, Niigata University Keyword: tetanus , dysphagia , tetanus immunoglobulin , critical illness of neurology pp.973-976
Published Date 2003/11/1
DOI https://doi.org/10.11477/mf.1406100551

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  • Abstract
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We describe two patients with generalized tetanus, a 60-year-old man and a 76-year-old woman, presenting with dysphagia as an initial symptom of the disease. Eighty percent of patients with generalized tetanus manifest dysphagia on admission to a hospital. However, dysphagia is rare as an initial symptom. Both our patients had dysphagia as their initial symptom, followed by neck stiffness and trismus. We made a diagnosis of generalized tetanus based on these neurological findings in the absence of an apparent episode of trauma. After the administration of tetanus immunoglobulin on admission, they recovered without exhibiting generalized convulsion, autonomic storm, or any other serious complications.

The vaccination of tetanus toxoid cannot maintain sufficient antibody titers more than ten years. Therefore, elderly people are considered susceptible to tetanus. We suggest that tetanus should be considered in the differential diagnosis of dysphagia particularly in elderly patients. We also suggest that treatment of tetanus should be initiated immediately, because tetanus still has a high mortality rate at present.


Copyright © 2003, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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