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A Case Report of Non-specific Ulcers of the Terminal Ileum M. Tada 1 , K. Matsumura 2 , A. Yamaguchi 2 , A. Nakanishi 2 , M. Okuda 2 , K. Shimamoto 2 , K. Kawai 3 1Kyoto First Red Cross Hospital 2Hoshigaoka Kosei Nenkin Hospital 3Department of Preventive Medicine, Kyoto Prefectural University of Medicine pp.803-806
Published Date 1979/6/25
DOI https://doi.org/10.11477/mf.1403107699

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  • Abstract
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 A 68-year-old man was admitted to our hospital with complaint of melena. He had three main signs of Behçet's recurrent aphthous stomatitis, scrotum ulcer and iritis. Clinical examinations showed positive occult blood but no significant bacillus or virus was found. Barium enema study and colonoscopy revealed irregularly shaped multiple ulcers at the ileocecal valve and terminal ileum.

 Ileocecal resection was performed because of the recurrence of melena. The resected specimen demonstrated multiple skipped irregular ulcers and scars, measuring from 0.4-0.4 cm to 1.0-3.0 cm, at the terminal ileum and ileocecal valve. Ileal mucosa was diffusely edematous. Histologically, these ulcers and scars, undermining to submucosa, were of nonspecific inflammatory process. The base of the ulcers showed granulation tissues containing marked inflammatory cellular infiltration but no granulomas.

 Although the ulcers were not similar to those of Behçet's disease which has grossly undermined appearance, clinical symptoms of the patient suggested Behçet's disease. Therefore, this inflammatory changes were strongly felt to be the early stage of intestinal Behçet's disease.


Copyright © 1979, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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