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A Case of Postoperative Hemorrhage Treated with Platelet Transfusion in a Patient with Essential Thrombocythemia Satoko IWAKIRI 1 , Yoko KINOSHITA 1,2 , Kazuya OMURA 1,2 , Motoko YUKIHIRA 1 , Yasuko BABA 1,2 , Kiyoyasu KURAHASHI 1,2 1Department of Anesthesiology, International University of Health and Welfare MITA Hospital 2Anesthesiology and Critical Care Medicine, International University of Health and Welfare School of Medicine Keyword: essential thrombocythemia , bleeding tendency , platelet disfunction , platelet transfusion pp.392-397
Published Date 2023/4/10
DOI https://doi.org/10.18916/masui.2023040016
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 Essential Thrombocythemia(ET)is likely to lead to thrombogenic and hemorrhagic tendencies. We report a case with difficulty in controlling postoperative hemorrhage.

 We admitted a 65-year-old man to our hospital complaining chiefly of hemifacial spasm. He was diagnosed with ET, and his previous doctor administered aspirin stat and hydroxyurea. He later developed acquired von Willebrand syndrome, and the doctor discontinued the aspirin. The patient had no clinical signs of thrombogenesis or hemorrhagic diathesis. Nevertheless, he had thrombocythemia. The patient underwent uneventful elective microvascular decompression surgery. Five and a half hours after surgery, the patient lost consciousness;a head CT scan revealed a substantial cerebellar hematoma. We applied hemostatic agents to the surgical site and administered fresh frozen plasma during an emergency craniotomy;however, we continued to experience difficulty with hemostasis. We finally transfused platelets, bearing in mind that impaired platelet function could be the cause of the bleeding. The surgeon completed the treatment and reduced the bleeding.

 Medical staff should consider platelet transfusion when a patient with ET experiences uncontrollable bleeding, even if the blood count shows sufficient platelets.


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電子版ISSN 印刷版ISSN 0021-4892 克誠堂出版

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