頭部に生じたfibroepithelioma of Pinkusの1例

A Case of Fibroepithelioma of Pinkus in the Head

はじめに

　Fibroepithelioma of Pinkusは基底細胞癌の特異型で，基底細胞癌と診断された中での割合は0.7 ％と報告されている 1）。また好発部位は体幹であり，頭頸部に生じるのは10 ％程度との報告がある 2）。今回われわれは，頭部に生じたfibroepithelioma of Pinkusのまれな症例を経験したので，文献的考察を加えて報告する。

　A 70-year-old female presented with a skin tumor on the right side of her head that had been gradually enlarging for several years. It was a 15×15 mm pale red and pedunculated nodule with smooth edges and a dome shape. We designed a spindle-shaped incision with 2 mm surgical margins and performed an excisional biopsy with a partial fat layer under local anesthesia. The histopathological findings demonstrated numerous thin anastomosing cords of atypical basaloid epithelial cells extending downward from the epidermis into the dermis within a fibromyxoid stroma. The lesion was diagnosed as fibroepithelioma of Pinkus, which is an unusual variant of basal cell carcinoma, with no specific clinical findings. The diagnosis of fibroepithelioma of Pinkus can be challenging because it often mimics benign entities such as soft fibromas, seborrheic keratoses, and intradermal nevi. Fibroepitheliomas of Pinkus are typically located on the trunk, but many body sites can be involved including the head, neck, groin, and leg. When clinicians encounter a pedunculated lesion, fibroepithelioma of Pinkus should be considered as a differential diagnosis.