雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Myocardial BMIPP scintigraphy:clinical utility in triglyceride deposit cardiomyovasculopathy(TGCV) Hideyuki Miyauchi 1 1Department of Cardiovascular Medicine Chiba University Graduate School of Medicine Keyword: 123I-BMIPP , 心筋洗い出し率 , 中性脂肪蓄積心筋血管症 , TGCV , 細胞内中性脂肪分解障害 pp.223-231
Published Date 2025/3/10
DOI https://doi.org/10.18888/rp.0000002857
  • Abstract
  • Look Inside
  • Reference

For over 30 years, 123I-BMIPP has been a pivotal tool for detecting abnormalities in fatty acid metabolism within cardiomyocytes, especially in cases of ischemic myocardial injury. With the emergence of the novel disease concept, triglyceride deposit cardiomyovasculopathy (TGCV), previously unrecognized aspects of BMIPP scintigraphy have come to light, expanding its clinical applications. TGCV is a rare intractable disorder characterized by intracellular triglyceride (TG) accumulation due to impaired TG lipolysis, leading to heart failure, arrhythmia, and coronary atherosclerosis. Despite normal serum TG levels, patients with TGCV exhibit intracellular TG accumulation in cardiomyocytes and vascular smooth muscle cells. BMIPP scintigraphy detects this abnormality by assessing washout rates (WR), where a rate below 10% constitutes an essential diagnostic criterion. This article elucidates the core diagnostic principles of TGCV using BMIPP WR and underscores its role as an invaluable clinical indicator.


Copyright © 2025, KANEHARA SHUPPAN Co.LTD. All rights reserved.

基本情報

電子版ISSN 印刷版ISSN 0009-9252 金原出版

関連文献

もっと見る

文献を共有