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Updated evidence of postoperative treatment for locally advanced head and neck squamous cell carcinoma Naomi Kiyota 1 1Kobe University Hospital Cancer Center Keyword: 術後化学放射線療法 , 術後再発高リスク , シスプラチン毎週投与法 pp.549-555
Published Date 2023/6/10
DOI https://doi.org/10.18888/rp.0000002355
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Standard treatment for postoperative high-risk patients with locally advanced head and neck squamous cell carcinoma is concurrent chemoradiotherapy(CRT)with cisplatin. As a result of a randomized phase Ⅱ/Ⅲ study of JCOG1008, CRT with weekly cisplatin at dose of 40 mg/m2 is non-inferior to CRT with 3-Weekly cisplatin at dose of 100 mg/m2 in terms of overall survival. Further development of postoperative treatment including the combination of immune check point inhibitors plus CRT is now ongoing.


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電子版ISSN 印刷版ISSN 0009-9252 金原出版

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