甲状腺乳頭癌胸膜播種の1例

Pleural Dissemination of Papillary Thyroid Carcinoma：Report of a Case

はじめに　われわれは甲状腺癌胸膜播種の1例を経験したので報告する．

A 67-year-old man was performed total thyroidectomy for stageⅣC papillary thyroid carcinoma with multiple lymph node and lung metastases. Five years and two months later, treatment with lenvatinib was started. Chest computed tomography （CT） six years and four months after the start of treatment revealed left pleural effusion. A pleural biopsy was performed under thoracoscopy. Histopathological findings showed papillary thyroid carcinoma, and the patient was diagnosed with pleural dissemination of thyroid cancer. Genetic test showed a positive BRAF V600E gene mutation. Treatment with dabrafenib and trametinib was initiated nine days after lenvatinib was discontinued.