肺原発滑膜肉腫の1例

Primary Pulmonary Synovial Sarcoma；Report of a Case

はじめに　滑膜肉腫は下肢に多く発生する軟部組織肉腫である．われわれは肺原発滑膜肉腫の1例を経験したので報告する．

A 66-year-old man was referred to our hospital for an abnormal shadow. Chest computed tomography（CT）showed a heterogeneous mass with well-defined border in the right S10and ipsilateral pleural effusion. Fluorodeoxyglucose-positron emission tomography（FDG-PET）showed the accumulation in the mass and pleural effusion. Right lower lobectomy with lymphnode dissection was performed for diagnosis and treatment. Histologically，the tumor was mainly composed of complicated spindle-shaped cells with extensive necrosis, showing a large number of nuclear fission images. Immunohistochemistry showed the tumor cells to be positive for cytokeratin AE1/AE3, Bcl-2, EMA, vimentin and negative for TTF-1, S-100, calretinin, CD34, being compatible with monophasic fibrous synovial sarcoma.