心膜悪性中皮腫の1例

Primary Pericardial Malignant Mesothelioma：Report of a Case

はじめに　悪性中皮腫は漿膜中皮より発生する悪性腫瘍であり，心膜に発生するものは1～2％と非常にまれである1）．われわれは心膜悪性中皮腫の1例を経験したので報告する．

A 67-year-old woman was referred to our hospital for cough and fever. Chest computed tomography （CT） showed some masses showing slightly enhanced effect in the pericardium. FDG-PET showed the accumulation of FDG in the masses. Thoracoscopic surgical biopsy was performed to establish the diagnosis. The histological study showed proliferation of short spindle-shaped cells surrounded by lymphocyte, and the spindle cells were immunohistochemically positive for cytokeratin AE1/AE3, WT-1, D2-40, CAM5.2, intelectin-1 and negative for CEA, TTF-1, napsin A, claudin-4, calretinin, MUC4, PAX8, CD30. These findings were compatible with epithelial pericardial malignant mesothelioma.