Nontuberculous Mycobacteriosis Resistant for Chemotherapy which was Suspected to Coexist with Lung Cancer Takeo Togo 1 , Jun Atsumi 1 , Kiyomi Shimoda 1 , Miyako Hiramatsu 1 , Tsutomu Yoshida 1 , Yuji Shiraishi 1 1Section of Chest Surgery, Fukujuji Hospital Keyword: nontuberculous mycobacteriosis (NTM) , lung cancer , SCC , surgical treatment pp.576-580
Published Date 2019/8/1
DOI https://doi.org/10.15106/j_kyobu72_576
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Nontuberculous mycobacteriosis (NTM) has been increasing recently. The treatment of choice of NTM is chemotherapy. Surgical treatment is sometimes indicated for patients with refractory NTM. When NTM lesion is enlarging despite of chemotherapy, there are 2 possibilities:intractable NTM and co-existing lung cancer. A 67-year-old male had been treated for fibro-cavitary NTM in the right upper lobe with chemotherapy. The cavitary lesion, however, was growing in spite of 6 months treatment. We suspected of a co-existing lung cancer because SCC level and standardized uptake value (SUV) in positron emission tomography (PET)-computed tomography (CT) were high. Bronchoscopy was performed but revealed no malignancy. He underwent a right upper lobectomy and the intraoperative pathology indicated NTM with no malignancy. After the operation, SCC levels decreased. This is a rare case with preoperative high SCC level which seemed to be related to NTM lesion.

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