血中CEA，AFPが高値であった肺原発肝様腺癌の1例

Hepatoid Adenocarcinoma of the Lung with High Serum AFP and CEA Values；Report of a Case

α-fetoprotein（AFP）は肝細胞癌や胚細胞性腫瘍，一部の消化管悪性腫瘍で高値を示す．Carcinoembryonic antigen（CEA）は腺細胞を含む臓器の悪性腫瘍や長期の喫煙で高値を示す．われわれは術前よりAFP，CEA高値を認め，他悪性腫瘍を認めず肺腫瘍切除によりAFP，CEA値の改善，良好な経過を得た肺原発肝様腺癌の1切除例を経験したので報告する．

A 60-year-old man exhibited an abnormal shadow in the right upper lobe. He was diagnosed with lung cancer by percutaneous computed tomography-guided lung tumor biopsy. Preoperative blood test showed high serum alpha-fetoprotein （AFP） and carcinoembryonic antigen （CEA） values. Right upper lobectomy was performed and histlogical diagnosis was AFP producing hepatoid adenocarcinoma with immunohistochemically positive HEP-PAR1. After the surgery, AFP and CEA values decreased to normal range.