末梢循環の動搖性に関する研究—第5報 正常人手指及び前腕のプレチスモグラムの分析

緒言

　末梢循環の研究に関しては既に長島等^1）が報告し，筆者も第1報〜第4報^2）に於て新しい方法による研究を発表し，特に第3報に於ては，極めて実施しやすい波形分析法を説明したので，その方法の記述は省略するが今回はそれ等の方法に基づいて，健康な成年男子について記録したプレチスモグラムの中から若干例をえらび，其等を分析し各種の知見が求められた。この方法によつて末梢循環系の状態の異同を判定する際，同じ性質の波形群とみなさねばならぬ例でも異つたものとして判定される危険も時にはみられ，又異つた性質のものでも同じと判定されることも起り得るから，各々の場合に観察可能な実験条件はなるべくくわしく記録して参照し，綜合的に判断することが必要なことは言う迄もない。波形分析法によつて求められた結論は従来分析法なしで経験的に下していた判定による結論と相俟つて事実の解釈を確かめる根拠となるのであり，決して前者のみで十分であり後者は無視されるとする訳ではない。

　Ⅰ Plethysmograms of the normal men.

　1. Plethysmogram of the finger and the forearm in normal man recorded on the smoked drum was analysed and it was found by inspection that the normal waves were to be cla-ssified into twenty types. These twenty types include not only the types already reported by various workers, also some new types which noticed for the first time by the present study.

　2. The curves obtained may be classified differently from the above, viz., from the standpoint of the physiological mechanisms responsible for its variations. The curves we-re classified into six types from such a standpoint.

　3. Several mathematical analysis (Fourier's analysis, correlagram, periodogram) were applied to the plethysmogram. Also a new method of wave analysls was worked out and applied to the wave.

　4. Plethysmograms of the right and left finger were compared and found to be very similar in pattern. The seasonal variations of the curves were also studied.

　Ⅱ Plethysmograms of the rabbit ear lobe.

　1. Plethysmograms of the ear lobe of the rabbit recorded on the smoked drum were studied, particulary as to its spontaneous variations.

　2. Analysis of these curves revealed the existence of the periodic variations as observed in man, though the wave pattern itself was somewhat different between rabbit and man.

　3. Taking the simplest case as an example, it was tried to interprete the wave from the hemodynamic principle under certain assumptions.

　Ⅲ The wave pattern analysis.

　1. A new method of wave analysis for the plethysmograms was described, based on the standpoint to consider, not the characteristics of the individual wave, but a group of such waves as a whole.

　2. This method for the α-waves of plethysmogram in the human forearm at the normal condition and under the caloric stimulation of the external meatus as well in the rabbit's ear lobe. The transformation matrices corresponding to the changes in pattern occurring spontaneously or brought about by the stimulation were calculated.

　Ⅳ Supplement (Experimental method and others)

　1. The experimental methods for plethysmography were discussed and some of its most important bearings were stressed.

　2. Causative mechanisms for the wavy fluctuations of plethysmogram were considered from the physiological standpoint, and various factors were discussed on the theoretical as well as experimental bases.

　Ⅴ The results of wave analysis applied on many examples.

　1. As far as the forearm volume were concerned, even "the normal controls" did not necessarily show strictly the same patterns all the time.

　2. Effect of cooling of the hand upon the forearm volume was found rather to be medi-ated by the arrival of cooded blood from the cooled hand, than by nervous reflex from the cooled hand.

　3. The curves taken simultaneously from the fingers of both sides were compared, and the patterns were found to be similar by analysis. The results of analysis of finger volu-me curves at 30℃ and at 21℃ respectively, revealed completely different patterns at these two temperatures.