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DNA Recombinant Research and You W. Patrick Monaghan , Marie Basilike , Nicholas Oleynik , Paul R. Sidelle , Susan L. pp.763-765
Published Date 1978/9/1
DOI https://doi.org/10.11477/mf.1543201701
  • Abstract
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DNA RECOMBINATION-the central dogma theory as proposed by Crick describes the flow of genetic information from the actual DNA molecule to the resultant phenotypic protein. Although some mechanics of this theory have recently been altered, the relation of DNA to protein is generally summarized by : DNA (transcription) RNA (translation) PROTEIN The techniques of recombinant DNA in the laboratory simulate many naturally occurring biological processes. The introduction of one or more foreign DNA strands, which become incorporated into a complex gene system, may alter certain properties of the cell, organ, or organism. For example, a bacterium would remain basically the same, but characteristics like pathogenicity, metabolism, and product exchange could be altered. In nature, the DNA strands are chromosome segments, and exchange of this material in chromosomes occurs during crossover. In meiosis during prophase I, the chromosomes are in a diploid condition and chiasmata or crossing over can be observed. The result is a recombined meiotic product from the exchange of genes on the chromosome.


Copyright © 1978, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1375 印刷版ISSN 0301-2611 医学書院

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