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BCG Hiroyuki Nishiyama 1 , Satoshi Mitarai 2 1International Programs, Japan Anti-Tuberculosis Association (JATA) 2Head of Bacteriology Division, Mycobacterium Reference Centre, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association (JATA) Keyword: BCG , 結核 , コッホ現象 pp.1328-1333
Published Date 2010/10/30
DOI https://doi.org/10.11477/mf.1542102442
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More than two billion people are infected with TB in the world. BCG vaccine is thought to prevent tuberculosis (TB). Actually, it can prevent the meningitis and disseminated TB among infants, but the efficacy for the adult pulmonary TB varies according to the clinical trials. Several reasons are proposed for the discrepancies, but still not determined. The duration of protection is also still under discussion. The BCG vaccination in Japan is considered safe, but the unfavorable reactions such as prolonged skin trouble, regional lymphadenitis and systemic BCG infection may occur. Koch's phenomenon and its analogue should be addressed in order to suspect TB infection. Several novel TB vaccines are now under development to cope with the problems of TB to which the current BCG is insufficient.


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電子版ISSN 1882-1367 印刷版ISSN 0485-1420 医学書院

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