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pp.97-103
Published Date 1962/2/20
DOI https://doi.org/10.11477/mf.1492202805

In order to afford a greater comfort to the patient during operation and to facil-itate the operative procedure on a smoo-ther basis preliminary medication is needed. For making a beter choice of agents in such a procedure various medications inteneded for this purpose are studied. Two hundred and thirty nine operative cases were tenati-vely divided in to 4 groups : To the first group, 101 cases the patients were given chlorpromazine, promethazine and operidine ; to the second group, 19 cases were given pro-methazine and operidine and in 62 cases, promethazine, ional and operedine. To the third group, 46 cases vesperine and operidine were given while, the fourth group, 10 cases were tried under operidine and rolfan.

It was found that the agents used in Group I were characterized by a strong anal-gesic action but they were also accompanied by many instances of side-reactions. Such agents may be well used in operations of the middle ear but their actions appeared to be too strong for operative procedures other than the ear. The agents used the Group Ⅱ appeared to be too weak for ear operations but well suited for nasal procedures. Those used in Group Ⅲ appeared to be suitable for ear operations when given in normal dosage and for other operations when the dosage was decreased. The use of synthetic narcotic and analgesic drugs in a combined usage seem to require a further study.


Copyright © 1962, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 印刷版ISSN 0386-9679 医学書院

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