2型糖尿病の薬物療法

Pharmacological Treatment for Type 2 Diabetes

Point

・糖尿病治療の目標は合併症の発症，増悪を防ぎ，糖尿病がない人と変わらない寿命とQOLの確保であり，そのなかで血管障害の発症・進展の抑制は重要である．

・合併症予防のための目標HbA1c値は7%未満だが，年齢や罹病期間，低血糖の危険性，臓器障害，サポート体制など，患者の病態や社会的背景などを考慮した個別の設定が望ましい．

・患者の糖尿病の病態，および糖尿病薬の最新の知見を基に，患者一人ひとりに合わせた治療の選択が重要である．

　Diabetes management primarily aims to achieve a life expectancy and quality of life similar to that of people without diabetes. The key to achieving this goal is the effective prevention and management of both the microvascular and macrovascular complications associated with diabetes. Although glycated hemoglobin levels of less than 7% are recommended to minimize complications, individual targets should be set considering variables such as age, duration of diabetes, risk of hypoglycemia, organ function, support system, general health status, and social background. Treatment decisions should be individualized according to each patient's diabetes status and guided by the latest evidence on diabetes pharmacotherapy.