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Next-Generation Sequencing Tests for Malignant Brain Tumors Yoshitaka NARITA 1 1Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital Keyword: がんゲノムプロファイリング検査 , がん遺伝子パネル検査 , 神経膠腫 , 膠芽腫 , next-generation sequencing , glioma , glioblastoma , FoundationOne® pp.19-28
Published Date 2022/1/10
DOI https://doi.org/10.11477/mf.1436204528
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 The cancer genome-profiling test is performed to analyze exome gene mutations, amplifications, deletions, fusion gene expression, etc. in tumor tissues with a next-generation sequencer to identify tumor-specific driver genes. The cancer genome-profiling test is covered by medical insurance for patients with malignant brain tumors in Japan, but it is limited to patients with good PS(performance status), considering the conditions for participation in clinical trials. The findings of the expert panel will create more opportunities to administer new therapeutic agents for clinical trials for malignant brain tumors.


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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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