肝細胞癌の頭蓋骨転移の1例

Cranial Metastasis of Hepatocellular Carcinoma: Case report

I．はじめに

　肝細胞癌は50-78％と高率に他臓器転移を来たすが，その多くは肺あるいは所属リンパ節であり^1），骨への転移は比較的まれで，しかもその多くは脊椎，肋骨，長管骨への転移である．頭蓋骨転移は剖検例でさえも骨転移のわずか6％に過ぎず^15），臨床例で発見されることは非常に少ない^{2-6,8,12,14,16）}．

　今回著者らは，頭皮下腫瘤で発症した肝細胞癌の頭蓋骨転移の1例を経験したので，文献的考察を加えて報告する．

A case of cranial metastasis of hepatocellular carcino-ma is reported. A 62-year-old man was admitted due to an elastic hard tumor in the left occipital region. On admission, neurological findings were normal and general condition was good. However, liver function was moderately abnormal. Plain craniography showed osteolytic change in the left occipital region. Compute-rized tomography showed bone destruction and well circumscribed high-density tumor in the left occipital region. The margin of the tumor was strongly en-hanced.