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Response to Antitumor Agents of Human Transplantable Glioma Implanted onto Chorioallantoic Membrane of Chick Embryo Osamu NAKAMURA 1 , Takuma SASAKI 2,3 , Hiroyuki UCHIDA 2 , Motohiro TANAKA 2 , Yoshio ENDO 2 , Kohei NISHIKAWA 2 , Masao MATSUTANI 1 , Kintomo TAKAKURA 4 1Department of Neurosurgery, Tokyo Metropolitan Komagome Hospital 2Chemotherapy Division, National Cancer Research Institute 3Department of Experimental Therapeutics, Cancer Research Institute, Kanazawa University 4Department of Neurosurgery, University of Tokyo Hospital Keyword: Brain neoplasms , Chemotherapy , Sensitivity test , Fertile chicken egg pp.353-357
Published Date 1988/4/10
DOI https://doi.org/10.11477/mf.1436202569
  • Abstract
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In case of chemotherapy against brain tumors, it is most important to choose suitable drugs for brain tumors, since human tumors have different drug sensi-tivity and growth. Heretofore, the nitrosourea-induced rat glioma cell, such as C6, or immunodeficient mice were usually used for predicting the drug sensitivity of brain tumors. We took notice of Murphy's system for the chemosensitivity test, in which a human tumor is transplanted into the chorioallantoic membrane ( CAM) of a chick embryo.


Copyright © 1988, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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