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I.はじめに
モヤモヤ病の初期変化と考えられる内頸動脈終末部の狭窄性変化の原因として,最近自己免疫抗体およびHLA抗体の関与が老えられてきている,今回,われわれは自己免疫抗体の検索から,モヤモヤ病における自己免疫抗体の関与の可能性を検討した.
The association of autoimmune antibody and HLA antibody has been dccumented concerning the patho-genesis of moyamoya desease.
In this paper, we study the autoimmune antibody in moyamoya disease and discuss its relationship with the pathogenesis. Autoimmune antibody was evaluated in 13 cases of moyamoya disease. The age distribution of the patients ranged from 13 to 55, with an average of 37 years. Eight were females, 5 males. Autoantibody was studied with native DNA (double strand DNA) and ANA (antinuclear anti-body). Antibody was noted in 3 cases (23%) in native DNA study, and 2 cases (15%) in ANA study.
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