多発性神経膠腫の2例

Two Cases of Multicentric Gliorna

I．はじめに

　脳腫瘍の診断はCT scanの善及により，この数年一段の進歩がみられているが，多発性腫瘍性病巣を認めた場合，安易に転移性脳腫瘍と診断され治療されている例が少なくない^3-5,11,14）．今回われわれは国立仙台病院において，CT scanで多発性病巣を認めたため，原発巣不明のまま転移性脳腫瘍と診断し治療したが，剖検脳の病理学的検索で多発性神経膠腫と診断された2例を経験した．わが国では多発性神経膠腫の報告は比較的稀であるが，本稿では自験例2例を中心に，臨床所見，治療，病理組織学的所見などにつき，若干の検討を加え報告する．

We reported two cases of multicentric glioma. Thefirst ease was 60-year-old female. In CT scan findings,separate mass lesions were observed in the right parieto-occipital area, left parietal lobe and left thalamic region.The second case was 53-year-old male. In CT scanfindings, separate mass lesions were observed in the rightfronto-parieto-temporal area and left frontal lobe. Thesetwo cases were considered to be metastatic brain tumor andradiation therapy and chemoimmunotherapy were performed.But in the postmortem examinations, both cases wereevident to be not metastatic brain tumor but glioblastomamultiforme.