Current Topics
A Microstereotactic Approach to Small CNS Lesions—Part II; Adjuvant Therapy Clinical Potential and Toxicity of Intraventricular Lymph Infusion
Skip Jacques
1
,
C. H Shelden
2
,
Cindy Clayton
2
1Huntington Institute of Applied Medical Research
2Department of Neurosurgery, Huntington Memorial Hospital
キーワード:
Thoracic duct
,
T-lymphocytes
,
Gliomas
,
Tumor immunotherapy
,
Immune surveillance
Keyword:
Thoracic duct
,
T-lymphocytes
,
Gliomas
,
Tumor immunotherapy
,
Immune surveillance
pp.615-622
発行日 1980年7月10日
Published Date 1980/7/10
DOI https://doi.org/10.11477/mf.1436201175
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A technique is described for adjuvant therapy of small central nervous system tumors after their removal. The feasibility of direct application of lymphocytes from the thoracic duct to the ventricular system of cats has been explored. Reduction of the antigenic mass by techniques described in part 1 of this paper is probably crucial.8). Patients with gliomas are known to have circulating tumorspecific lymphocytes which may not have direct access to the CNS. This study demonstrated no toxicity from the chronic intraventricular infusion of thoracic duct lymph in cats.
Copyright © 1980, Igaku-Shoin Ltd. All rights reserved.