Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
- 参考文献 Reference
Ⅰ.はじめに
無症候性髄膜腫は,画像診断の発達でその発見の頻度が増加したため,1990年より原発性脳腫瘍の中で髄膜腫が最も頻度の高い腫瘍となった14).必然的に無症候性髄膜腫の手術例も増加した.無症候性髄膜腫の手術適応に関してはおおまかな基準はあるものの12),細部については髄膜腫の自然歴や治療成績を背景にした議論が現在も続いている15).
これまで脳腫瘍の治療成績は治療後の死亡率や合併症の割合によって,また治療後の患者の身体活動度についてはKarnofsky performance statusやGlasgow Outcome Scaleのような,医療者側で判定する数値によって評価されていた.しかしこれらの数値では,患者自身の健康観は反映されない.患者を主体とした医療が叫ばれる中,近年は患者の主観的な健康指標も治療成績として重要になりつつある.
筆者らは無症候性髄膜腫の術後患者に対し,健康関連QOL(quality of life)尺度のMOS Short-Form 36-Item Health Surbey(SF-36(R))と不安とうつの尺度であるHospital Anxiety and Depression Scale(HADS)を用いて,生活の質(QOL)の評価を行った.そのうえでQOL低下の要因や評価の意義について論じた.
The aim of our study was to assess the quality of life (QOL) of patients operated on for asymptomatic meningioma and to assess the correlation between QOL and operative complications. Of 21 surgically treated patients, 6 (28.6%) presented with persistent neurological impairments or events considered to be treatment-related. Seventeen patients participated in the QOL survey using MOS Short-Form 36-Item Health Survey (SF-36(R)) for health-related QOL issues and the Hospital Anxiety and Depression Scale (HADS) for anxiety and depression assessment. The mean scores for each of the 8 domains of SF-36(R) were comparable with these of a Japanese reference population. When we divided the patients into 2 groups according to the degree of headache, activity of daily living, or complications, the QOL of patients with persistent headache declined in the SF-36(R) domains related to physical function and vitality. Minor neurological impairments developed by 4 patients did not affect their QOL. In conclusion, surgery for asymptomatic meningioma has no negative impact on postoperative QOL if the surgical complications are minor. On the other hand, physical activities in some patients were hampered due to persistent headache. Besides the treatment-related morbidity and mortality rates, QOL issues should also be included in treatment indications for asymptomatic meningioma.
Copyright © 2007, Igaku-Shoin Ltd. All rights reserved.