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Oncogenicity of BK virus in Syrian hamsters Seijiro UCHIDA 1 1Department of Viral Infection, Institute of Medical Science, University of Tokyo pp.252-254
Published Date 1980/4/10
DOI https://doi.org/10.11477/mf.1431905156
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Abstract

 Newborn hamsters were Inoculated Intracerebrally with a series of purified and concentrated BK virus samples originating from a single stock of Gardner's original strain. Most of the hamsters developed various tumors 3~9 months later. The frequent types of tumors were ventricular tumors, malignant insulinomas and osteosarcomas. The incidence of insulinomas varied greatly with the virus sample; the two samples that showed the highest incidences (47% and 92%) originated from one parental virus stock, and all the other samples with the lower incidences (0~9%) originated from another ancestral stock.


Copyright © 1980, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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