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Cerebral edema due to radiation injury:Incidence,mechanism,and preventive strategy for cerebral edema aften radiosurgery Motohiro Hayashi 1 1Department of Neurosurgery, Tokyo Women's School of Medicine Keyword: ガンマナイフ , 放射線障害 , 脳浮腫 , 転移性脳腫瘍 , 脳動静脈奇形 , 側頭葉てんかん pp.271-279
Published Date 2006/4/10
DOI https://doi.org/10.11477/mf.1431100135
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Stereotactic radiosurgery(SRS)is not conventional radiation therapy. SRS leads destructive changes to the pathological tissue which is involved within the target. Additionally, the surrounding normal brain tissue would be also damaged, because SRS is higher energy radiation therapy because of single-high dose radiation. When we have to perform SRS,“target radiation volume”and“radiation dose”should be considered as the most important treatment factors to provide good prognosis to the patients. If both two factors are too large, the treatment effectiveness will be better. However, there will be much more risky to develop into“severe brain edema in the surrounding normal brain tissue”. In this article, we'd like to demonstrate the represented diseases which have problem to be easier to trigger the development of“perifocal edema”after SRS;large“metastatic brain tumor”, huge“arteriovenous malformation”, and“mesial temporal epilepsy”as one of recent indication in the field of functional radiosurgery.

 We'd like to demonstrate our latest treatment strategy which was considered very much to avoid the development of“perifocal edema”after SRS, in order to provide better QOL to the patients.


Copyright © 2006, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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