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Clinical Application of Transcutaneous Auricular Vagus Nerve Stimulation Takamichi Yamamoto 1 1Department of Neurosurgery, Comprehensive Epilepsy Center, Seirei Hamamatsu General Hospital Keyword: 迷走神経刺激 , 経皮的 , 耳介神経 , てんかん , 薬剤抵抗性 , vagus nerve stimulation , transcutaneous , auricular branch , epilepsy , drug resistant pp.991-995
Published Date 2022/8/1
DOI https://doi.org/10.11477/mf.1416202166
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Abstract

Transcutaneous auricular vagus nerve stimulation (taVNS) refers to stimulation of the vagus nerve through the skin of the left cymba conchae and is a unique strategy that is investigated as a useful therapeutic approach for a variety of conditions including epilepsy, depression, cardiac diseases, tinnitus, and migraine. A randomized double-blind clinical trial was performed in patients with drug-resistant epilepsy. Although several pilot studies were performed before this trial and showed that taVNS was safe, well tolerated, and feasible for long-term treatment, no statistically significant difference was observed between the high- and low-stimulation groups, and further studies are warranted to gain a deeper understanding of this subject. A tingling sensation or pain at the site of stimulation is the most common adverse effect associated with taVNS. Therefore, intermittent stimulation, ranging from 30 minutes to several hours, is provided during each session several times a day. Currently, taVNS is not approved for insurance coverage by the Japan Ministry of Health, Labour, and Welfare. Further studies and investigations are necessary in the near future.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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