Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
- 参考文献 Reference
新型コロナウイルス(SARS-CoV-2)感染症(COVID-19)は脳炎・脳症,脱髄疾患,ギラン・バレー症候群などの神経合併症が報告されてきた。感染後数日〜数週間で運動異常症が発症する例もあり,自己免疫性機序が想定されている。またCOVID-19に対するワクチン接種が進み,副反応としてギラン・バレー症候群などの報告があるが,因果関係はいまだ不明である。本論ではCOVID-19感染症で生じるミオクローヌス,オプソクローヌス,パーキンソニズム,小脳失調など運動異常症の病態,SARS-CoV-2ワクチンとの関連につき概説する。
Abstract
The new coronavirus SARS-CoV-2 infection (COVID-19) has caused many casualties, mainly respiratory infections. However, it has also caused several neurological disorders including encephalitis/encephalopathy, demyelinating disease, Gullain-Barré sydrome etc. In addition, it has been clarified that movement disorders develop within a few days to weeks after infection. Vaccination for COVID-19 has progressed, but autoimmune neurological complications have also been reported. Although a causal relationship is suspected over time, this paper describes the pathophysiology of movement disorders such as myoclonus, opsoclonus, parkinsonism, and cerebellar ataxia, which are relatively common in COVID-19 infections, and their relevance to the SARS-CoV-2 vaccine.
Copyright © 2022, Igaku-Shoin Ltd. All rights reserved.