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いまだ世界中で猛威を振るっているCOVID-19の感染者数の増加に伴い,COVID-19関連神経学的合併症の報告が増加した。特にCOVID-19によって血栓形成促進状態が惹起され,脳梗塞発症リスクを高めることが示された。一方で,2022年において,COVID-19合併脳卒中の頻度が蔓延当初よりも少ないなど,蔓延当初の報告とやや異なる点も散見され始めている。本論では,COVID-19と脳卒中,特に脳梗塞との関連,COVID-19合併脳卒中の病態および予後について,最新の論文を参考に述べる。
Abstract
As the number of COVID-19 cases continues to rapidly increase worldwide, a corresponding increase in COVID-19-induced neurological complications is being observed in clinical practice. COVID-19 is shown to trigger a pro-thrombotic state, which increases the risk of ischemic stroke. However, the incidence of COVID-19-induced ischemic stroke in 2022 was lower than that observed during the early stages of the pandemic. In this chapter, we describe the association between COVID-19 and stroke and the pathophysiology and prognosis of stroke in patients with COVID-19, together with a review of the latest literature.
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