Neurocognitive Disorders Other Than Alzheimer Disease: Vascular Dementia Mari Yoshida 1 1Institute for Medical Science of Aging Aichi Medical University Keyword: 血管性認知症 , 脳小血管病 , CADASIL , CARASIL , 脳アミロイド血管症 , vascular dementia , cerebral small vessel disease , cerebral amyloid angiopathy , CAA pp.517-531
Published Date 2018/5/1
DOI https://doi.org/10.11477/mf.1416201034
  • Abstract
  • Look Inside
  • Reference


Vascular dementia involves several mechanism of pathogenesis. Cerebral small vessel diseases play a central role in vascular dementia, including sporadic cerebral small vessel diseases, cerebral autosomal-dominant or autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL or CARASIL), cerebral amyloid angiopathy, and amyloid β-related angiitis. Although these diseases have different pathomechanisms, chronic white matter hypoperfusion contributes to development of neuronal dysfunction as a common pathway in vascular dementia. Vascular dementia also may affect the cognitive decline observed in neurodegenerative diseases such as Alzheimer's disease.

Copyright © 2018, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院