Brain Function and White Matter Hiroaki Wake 1 , Daisuke Kato 1 1Division of Homeostatic Development, National Institute for Physiological Sciences, National Institutes of Natural Sciences Keyword: 白質 , オリゴデンドロサイト , 神経伝導速度 , 髄鞘 , 情報処理 , white matter , oligodendrocyte , conduction velocity , myelin , information processing pp.505-512
Published Date 2015/4/1
DOI https://doi.org/10.11477/mf.1416200167
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Accumulated evidence shows that neural information processing takes place in superficial layers of the brain called the gray matter. Synapses, which connect different neurons reside in the gray matter and are considered the major components of information processing and plasticity. On the other hand, myelinated axons lie beneath the gray matter. These bundles of cables connect neurons in the different brain regions to form functional neural circuits. Myelinated axons were of little of interest to neuroscientists and have long been ignored in the formation of functional neuronal circuits. Recent evidence shows that myelin formed by oligodendrocytes shows plastic changes depending on neuronal activity. In this issue, we discuss the plastic changes of myelin and its functional role in learning and training.

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