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Volumetry of Cerebral Gray and White Matter Using VSRAD® Hiroshi Matsuda 1 1Integrative Brain Imaging Center, National Center of Neurology and Psychiatry Keyword: MRI , 体積測定 , VSRAD® , 灰白質 , 白質 , MRI , voxel-based morphometry , VSRAD® , gray matter , white matter pp.487-496
Published Date 2015/4/1
DOI https://doi.org/10.11477/mf.1416200165
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Abstract

Voxel-based morphometry (VBM) using structural brain MRI has been widely used for the early and differential diagnosis and evaluation of disease progression in neuropsychiatric diseases. VBM of MRI data comprises segmentation into gray matter, white matter, and cerebrospinal fluid partitions; anatomical standardization of all the images to the same stereotactic space using linear affine transformation and further non-linear warping and smoothing; and finally performing statistical analysis. Stand-alone VBM software using SPM8 plus DARTEL running on Windows (Voxel-based Specific Regional analysis system for Alzheimer's disease, VSRAD®) has been developed as an adjunct to the clinical assessment. This software provides a Z-score map as a result of the comparison of the patient's MRI with a normal database.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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