特発性後腹膜線維化症および尿路吻合部狭窄に対する柴苓湯の使用経験

Clinical Efficacy of Sairei-to to the Idiopathic Retroperitoneal Fibrosis and the Ureteral Stricture after Reanastomosis:Report of Three Cases

　特発性後腹膜線維化症2例および尿管—回腸導管吻合部狭窄1例に柴苓湯を投与し，3例とも水腎症が改善した。前者は新鮮例1例，ステロイド治療後の再発例1例で，後者は再吻合後の狭窄予防に使用した。柴苓湯は内因性ステロイド分泌促進，線維芽細胞増殖抑制などの作用があり，泌尿器科領域でも種々の線維化疾患への投与が試みられている。今回，尿路吻合部狭窄に対しても有効性が示唆された。

Sairei-to which promotes the secretion of the corticoid,and inhibits the fibroblast proliferation, was given to twopatients with idiopathic retroperitoneal fibrosis and onepatient with ureteral stricture after reanastomosis and wasclinically effective in all three cases. Case 1: a 57-year-old man with the idiopathic retroperitoneal fibrosis. Hy-dronephrosis became improved after 9-month-medicationof Sairei-to. Case 2: hydronephrosis has been improvedby Sairei-to in a 72-year-old man with recurrent idiopathicretroperitoneal fibrosis after the treatment by corticoidpreparation.