ダウン症候群に合併した精巣腫瘍

A Case of Testicular Tumor Associated with Down's Syndrome

　症例は32歳，男性。生来ダウン症候群と診断され，左陰嚢内容の無痛性腫大を主訴に入院となった。HCG-βと神経特異エノラーゼの上昇を認め，血清LH,FSH濃度も上昇していた。左高位精巣摘除術を施行し，病理検査でセミノーマと診断した。対側の萎縮した精巣の生検も行ったが，悪性所見は認めなかった。他に転移を認めなかったため，追加治療は施行せず経過観察中である。

A 32-year-old male with Down's syndrome was admitted to our hospital with the chief complaint of a painless intras-crotal mass, which had been increasing in size. The serum level of HCG-β and neuron-specific enolase were elevated. Laboratory studies demonstrated elevated LH and FSH concentration. Left high inguinal orchiectomy was per-formed and the pathological findings showed a seminoma. Abnormal germ cells were not found in a biopsy specimen from the right atrophic testis. No adjuvant therapy was administered because the cancer seemed to be localized.