Aniridiaに合併したWilms腫瘍

WILMS' TUMOR IN A CHILD WITH CONGENITAL ANIRIDIA

緒言

　Congenital aniridia（以下aniridia）にWilms腫瘍が高率に発生することは，1968年Fraumeniら^1）の報告によつて識者の注目するところとなつた。しかし，aniridiaそのものが稀な疾患であるためか，一般の関心を集めるまでには至つていない。

　われわれはaniridiaの男児例を生後8ヵ月以降定期的に観察し，症状発現以前にWilms腫瘍の発生を確かめ，根治的処置によつて良好な結果を得たので，ここにその経験を述べ，若干の考察を加えて報告する。

A boy, who had a congenital aniridia and an undescended testis, had several pyelographies since 8-month old because of the increasing risk that Wilms' tumor could develop. When he was 2-year 2-month old, IVY and renal arteriography showed a space-occupying lesion diagnosed as a left Wilms' tumor.

The tumor was completely removed by radical nephrectomy. Actinomycin D has been administered internittently after surgery. The child is now 3-year 5-month old and healthy without any evidence of metastasis, recurrence or contralateral occurrence.