ROTHMAN-MAKAI SYNDROME Chiaki NISHIYAMA 1 1Department of Dermatology, Nihon University School of Medicine pp.883-886
Published Date 1970/9/1
DOI https://doi.org/10.11477/mf.1412200706
  • Abstract
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A 21-year-old man having this disease for 4 months' duration was reported. Past history failed to prove trauma, foreign body injection and steroid therapy.

Skin lesions were subcutaneous, elastic, hard, walnut-sized nodules with slight erythema arranged in on arc on the chest and abdomen. They were attached to the skin but movable on to the underlying layer and were free from pain spontaneously or on pressure. Results of laboratory tests were within normal limits.

Histologic specimen showed granulomatous panniculitis with fat necrosis, and an infiltrate composed of lymphocytes, histiocytes, foam cellsand giant cells. An intracutaneous test with staphylococcus toxoid was positive.

The nodules began to disappear 4 weeks after the starting of oral administration of a long-acting sulfonamide and disappeared completely without persistent pigmentation, atrophy and depression. No recurrence was noted.

Copyright © 1970, Igaku-Shoin Ltd. All rights reserved.


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