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GRAYISH-WHITE FLECKS IN DARIER'S DISEASE Takahumi MORISHIMA 1 , Terunobu HAYASHI 1 1Department of Dermatology, Nihon University School of Medicine pp.253-260
Published Date 1967/3/10
DOI https://doi.org/10.11477/mf.1412200112
  • Abstract
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A 17-year-old boy of Darier's disease with typical clinical lesions on the head, neck, axillae, supra- and infraclavieular regions, middle of the back and hypogastirium is reported. Except these lesions, there scattered grayish-white flecks on the extremities which Hidaka called "primary lesions."

In this case, these grayish-white flecks did not show any tendency to transform into typial verrucous lesions of Darier's disease in spite of the existence of the disease for 7 years, and the clinical picture of the flecks lacked seasonal changes. The histopathology showed no pathognomonic findings of Darier's disease, while miliaria-like red papules occurring in the early stage of a recurred eruption after dermabrasion therapy showed a typical histologic picture. These flecks are not common and usual in Darier's disease, but very few cases with them have been reported in the literature.

Considering all the above-mentioned facts, the authors can not agree with the opinion that these flecks is a common primary change, although Hidaka and Neuman reported that they proved in their cases the transition from the grayish-white fleckle to typics verrucous papules of Darier's disease. The flecks are considered not to be primary lesions, but to show an abortive form of the lesions in Darier's disease, as well as acrodermatitis verruciformis-like lesions.


Copyright © 1967, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1324 印刷版ISSN 0021-4973 医学書院

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