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Japanese

A case of granulomatosis with polyangiitis of the maxillary sinus requiring differentiation from invasive fungal infection and malignant tumor Yosuke Okinaka 1 , Kazuma Sugahara 1 , Hironori Fujii 1 , Makoto Hashimoto 1 , Soutai Kimura 2 , Hiroshi Yamashita 1 1Department of Otolaryngology, Yamaguchi University Graduate School of Medicine Keyword: 多発血管炎性肉芽腫症 , 骨破壊 , 真菌 pp.279-284
Published Date 2023/3/20
DOI https://doi.org/10.11477/mf.1411203277
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 Granulomatosis with polyangiitis(GPA)often develops with nasal symptoms. GPA without nasal symptoms is difficult to diagnose. We experienced a case of granulomatosis with polyangiitis of the maxillary sinus requiring differentiation from invasive fungal infection and malignant tumor.

 A 71-year-old woman presented with left cheek pain. CT tomography revealed a soft tissue shadow accompanied by bone destruction of the maxillary sinus, although her nasal findings were normal. Invasive fungal infections and malignant tumors were preoperatively suspected. Endoscopic sinus surgery was performed, and GPA was diagnosed. If we focused on preoperative lung lesions, we may have been able to make an accurate preoperative diagnosis. She was treated with Rituximab and Methylprednisolone at the Department of Internal Medicine of our hospital. She has been in remission for approximately 6 months since the surgery.


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電子版ISSN 1882-1316 印刷版ISSN 0914-3491 医学書院

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