化学療法が著効を示した嗅神経芽細胞腫の1例

Chemotherapy for Olfactory Neuroblastoma―A Case Report

I．はじめに

　嗅神経芽細胞腫は嗅神経上皮を発生母地とし，鼻腔嗅部に好発する悪性腫瘍である。その発生頻度は鼻腔腫瘍の約3％である^1）。治療法として，一般的には手術と放射線療法の併用が勧められている^1）。一方，化学療法については有効であるとの報告も散見される^1）。

　今回われわれは，化学療法が著効を示した嗅神経芽細胞腫の1例を経験したので報告する。

　A 32-year-old male presented with bloody post nasal drip,and reddish mass was found in the right nasal cavity. The mass was pathologically diagnosed as olfactory neuroblastoma. The tumor was limited to the nasal cavity and paranasal sinuses. After a course of a combined chemotherapy consisting of CDDP and 5-FU,a complete remission was achieved. After two courses of combined chemotherapy and radiation were performed,but additional craniofacial surgery was not needed. The patient became free from disease with full function for a year after initiating chemotherapy.