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Treatment of cytomegalovirus retinitis with ganciclovir Shigeru Kishi 1 , Keizo Hosogi 1 , Hidenori Hayashi 1 , Akihiko Tamai 1 , Kenji Niiya 2 , Yoshito Iwahara 2 , Isao Miyoshi 2 1Dept of Ophthalmol, Kochi Med Sch 23rd Dept of Medicine, Kochi Med Sch pp.227-231
Published Date 1990/3/15
DOI https://doi.org/10.11477/mf.1410908068
  • Abstract
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Acute cytomegalovirus retinitis developed bilaterally in 2 patients. One was a 40-year-old male with AIDS. We treated both cases with intravenous ganciclovir. The response was prompt with resolu-tion of retinal exudates in both cases. The retinitisrelapsed in the second case with the visual acuity reduced to no light perception in both eyes. Leucopenia developed in the first case, necessitat-ing temporary discontinuation of ganciclovir.

Intravenous ganciclovir thus appeared to be effective in treating cytomegalovirus retinitis. Pre-vention of relapse through adequate maintenance of the drug seemed to be crucial for the final fair outcome.


Copyright © 1990, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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