落屑症候群における隅角所見の統計的観察

Gonioscopic features of pseudoexfoliation syndrome

　落屑症候君羊196例の341眼の隅角を検索した。同世代の白内障患者180例360眼を対照とした。6時方向の隅角の色素沈着は，落屑症候群眼では対照眼よりも顕著であり（p＜0.001），特に緑内障発症眼で強かった。片眼落屑眼89例では，落屑眼で色素沈着が僚眼よりも強く（p＜0.001），さらに僚眼での色素沈着が対照眼よりも有意に強かった（p＜0.001）。Sampaolesi線は，落屑眼で多く（p＜0.001），落屑眼のうち高眼圧がある眼では頻度が低かった。狭隅角は，落屑では対照眼よりも多く，特に緑内障眼に多かった。落屑症候群では色素沈着とSampaolesi線の存在が特徴的な隅角所見であり，緑内障の発症に色素沈着と狭隅角が関与していることが推定された。

We evaluated the gonioscopic features of 341 eyes of 196 cases with pseudoexfoliation syndrome. Age-matched 360 eyes of 180 cases with cataract served as control. Angle pigmentation at 6 o'clock position was significantly more intense in the affected eyes than in controls (p ＜ 0.001) and particularly in eyes with glaucoma. In 89 unilaterally affected cases, angle pigmentation was significantly more intense in the affected than in the fellow eyes (p ＜ 0.001) . Angle pigmentation in the unaffected fellow cases was more intense than in controls (p ＜0.001) . The incidence of Sampaolesi line was greater in eyes with pseudoexfoliation than in controls (p ＜ 0.001) and was less in eyes with ocular hypertension. Nerrow chamber angle was more frequent in affected eyes than in controls. This feature was more apparent in eyes with glaucoma. The findings show that eyes with pseudoexfoliation are characterized by hyperpigmentation and Sampaolesi line in the chamber angle and that both features may be involved in pseudoexfoliation glaucoma.