眼窩および眼球付属器の悪性リンパ腫の9症例

Nine cases of malignant lymphomas of the ocular adnexa

　過去12年間に和歌山県立医科大学眼科で治療された，眼窩および眼球付属器のB細胞性悪性リンパ腫の9症例を報告した。全例とも非ホジキンリンパ腫，8例は眼窩原発性で初診時stage I，残り1例は不明であった。3例は，経過中にstage IIに進展した。分類別にみると，3例はmucosa associatedlymphoid tissue （MALT） lymphoma，2例はlarge cell lymphoma,1例はsmall lymphocytic lymphomal1例はmantle zone lymphoma,1例はintermediate lymphocytic lymphoma （ILL），1例はlymphop-lasmacytomaであった。

　3例はまず放射線療法を施行し，そのうち2例は再発した。別の3例はまず化学療法を施行し，そのうち1例は再発した。1例はステロイド結膜下注射で経過観察中である。2例は経過観察のみ行っている。進行は緩徐であるが，完全な治瘉は容易ではないと考えられた。

A clinicopathological review was made on nine cases of B cell malignant lymphoma of the ocular adnexa during the foregoing 12-year period. All cases were non-Hodgkin lymphoma. Eight cases were primary and in stage I . Three cases were in stage II. No detail was known in one case. Histopathologically, there were 3 cases of MALT lymphoma, 2 cases of large cell lymphoma, and one case each of small lymphocytic lymphoma, lymphoplasmacytoma and intermediate lymphocytic lymphoma (ILL) . Three cases were treated by radiation followed by recurrence in 2 cases. Three cases were treated by chemotherapy followed by recurrence in 1 case. One case was treated by systemic corticosteroid. Three cases were not treated. The findings suggest that malignant lymphoma of the ocular adnexa has a tendency to slowly develop and that complete cure is difficult.