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Clinical manifestations of 6 syphilitic uveitis cases diagnosed at Dokkyo Medical University Haruka Matsumoto 1 , Mayumi Nagata 1 , Shigenari Suzuki 1 , Tadashi Senoo 1 1Department of Ophthalmology, Dokkyo Medical University Hospital pp.1336-1342
Published Date 2023/10/15
DOI https://doi.org/10.11477/mf.1410214941
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Abstract Purpose:To discuss the clinical manifestations and courses of 6 syphilitic uveitis in six cases diagnosed at our institution which initially manifested with ocular symptoms.

Methods:Six patient who presented to out institution between November 2018 to April 2022 with unexplained uveitis and were diagnosed with syphilitic uveitis were retrospectively studied. Nine eyes of two men and four women(age, 55±5.6 years)were analysed.

Results:All patients were diagnosed with secondary or tertiary syphilis. Cerebrospinal fluid was examined in five cases, with positive results in three(60%). Of the three cases, neurological symptoms were observed in one. We administrated antiluetic therapy to five patients, all of whom experienced improvement in visual acuity, which was maintained at logMAR −0.1. One patient refused treatment and remained untreated.

Conclusion:Neurosyphilis was observed in most of our patients diagnosed with syphilitic uveitis. It is important to assess syphilitic uveitis when evaluating uveitis with unexplained origin, and to provide multidisciplinary care upon diagnosis.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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