雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Intractable uveitis with tattoo-associated sarcoidosis Satoshi Koide 1 , Ena Suzuki 1 , Hiroaki Amari 2 , Keigo Natsume 3 , Kumiko Mokuno 1 1Department of Ophthalmology, Kariya Toyota General Hospital 2Department of Ophthalmology, Asahi University Hospital 3Department of Ophthalmology, Nagoya University Graduate School of Medicine pp.767-773
Published Date 2023/6/15
DOI https://doi.org/10.11477/mf.1410214828
  • Abstract
  • Look Inside
  • Reference

Abstract Background:Tattoo-associated sarcoidosis presents with sarcoid-like granulomas in tattoos and clinical symptoms of systemic sarcoidosis, which can complicate uveitis. Here, we report a case of intractable uveitis with suspected tattoo-associated sarcoidosis.

Case:A 30-year-old woman presented to the internal medicine department of our hospital with fever and right inguinal lymphadenopathy in January 20XX, and visited the ophthalmology department with pain and vision loss in her right eye 3 months later. High laser flare values, tent-shaped peripheral anterior synechiae, and snowball-like vitreous opacity were observed in both eyes. Fluorescein angiography revealed bilateral optic nerve papillary hyperfluorescence and mottled vascular leakage. Serum soluble interleukin-2 receptor and lysozyme were elevated. Gallium scintigraphy showed accumulation in both axillary and right inguinal lymph nodes. Biopsy of her tattooed skin showed sarcoid-like granulomas including granules suggestive of tattoo pigments. She was treated with betamethasone sodium phosphate in her right eye, prednisolone(PSL), and excision of the tattoo. The PSL was tapered over 4 months with improvement of clinical symptoms. She presented with progressive vision loss in both eyes with macular edema after a month. Sub-Tenon's triamcinolone acetonide(STTA)was performed in the right eye and PSL was resumed. Cataract surgery was performed in August 20XX+1. Bilateral macular edemas recurred and multiple STTA injections were performed. In May 20XX+3 she was started on adalimumab. Since then, no recurrence of macular edema in both eyes has been observed.

Conclusion:Tattoo is a possible cause of uveitis associated with sarcoidosis. Our report suggests that adalimumab is effective in cases resistant to steroid therapy.


Copyright © 2023, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

関連文献

もっと見る

文献を共有