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Incidence and family history of outpatients with retinitis pigmentosa in Oki Island, Shimane Prefecture Yutaka Oomatsu 1 , Kazuki Matsuura 2 , Yuki Terasaka 2 , Yuji Sasaki 3 , Yoshitsugu Inoue 4 1Department of Ophthalmology, Oki Hospital 2Department of Ophthalmology, Nojima Hospital 3Department of Ophthalmology, Sanin Rosai Hospital 4Dvision of Ophthalmology and Visual Science, Tottori University Hospital pp.655-658
Published Date 2018/5/15
DOI https://doi.org/10.11477/mf.1410212683
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Abstract Background:Oki archipelago is located about 50 km north of Shimane peninsula, Shimane Prefecture. The islands are populated by about 20,000 inhabitants. There is a possibility of high incidences of hereditary disorders, including retinitis pigmentosa(RP), among inhabitants of the archipelago.

Purpose:To report the incidence and family history of outpatients with RP at Oki Hospital as compared with findings at clinics in the mainland of Shimane Prefecture.

Method:This study was made on outpatients who visited Oki Hospital, Sanin Rosai Hospital, Nojima Hospital, and Chizu Hospital during 2016.

Results:There were 143 patients who were diagnosed with RP out of a total of 12,315(1.16%)outpatients during 2016 at Oki Hospital. There were 1 out of 8,498 outpatients(0.01%)at Sanin Rosai Hospital, 25 out of 16,700 outpatients(0.15%), and 1 out of 2,698 outpatients(0.04%)at Chizu Hospital. Incidence of RP was significantly higher at Oki Hospital than at other 3 hospitals(p<0.01). A total of 32 patients responded to questionnaires at Oki Hospital. There were 19 patients(59.4%)who reported the presence of relatives with RP, including 16 patients(50.0%)with relatives with RP in the second degree. There was no case with family history of consanguineous marriage.

Conclusion:Incidence of RP was significantly higher among outpatients of Oki Hospital than 3 hospitals in Shimane Prefecture in the mainland.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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