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Two cases of sclerouveitis positive for anti-neutrophil cytoplasmic antibody(ANCA) Mari Sorita 1 , Atsushi Yoshida 1 , Hidetoshi Kawashima 1 1Dept of Ophthalmol, Jichi Med Univ pp.569-574
Published Date 2015/4/15
DOI https://doi.org/10.11477/mf.1410211308
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Abstract. Purpose:To report 2 cases of sclerouveitis positive for anti-neutrophil cytoplasmic antibody(ANCA). Cases and Findings:Both were females aged 69 and 74 years respectively. Both were unilaterally affected and showed signs of necrotizing sclerouveitis. One case showed vitreous opacity and snowbank lesion. Hematologically, C-ANCA(PR3-ANCA)was elevated in one case and P-ANCA(MPO-ANCA)in the other. One was diagnosed with granulomatosis with polyangiitis and the other with microscopic polyangiitis. Systemic corticosteroid in both cases and azathioprine in one led to improvement of ocular and systemic lesions and lowering of ANCA. Conclusion:Examination of ANCA in the circulating blood was essential in the diagnosis and treatment of ANCA-positive sclerouveitis.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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