両眼角膜移植症例の検討

Results of bilateral penetrating keratoplasty

　1974年1月から1987年3月までに岩手医大眼科で行った全層角膜移植312眼のうち，両眼に移植手術が成された20例40眼について検討を行った．

　1．20例40眼の透明治癒率は62.5％であった．疾患別では円錐角膜が100％，角膜ジストロフィーが37.5％，角膜白斑が58.3％であった．

　2．両眼に角膜移植を受けた症例において，移植第1眼の透明治癒率は55.0％，第2眼は70.0％であったが，推計学的には有意差はなかった．

　3．両眼角膜移植症例の移植第1眼と第2眼において，移植間隔が1年以内の透明治癒率は44.4％，1年以上では77.3％であり，手術間隔を1年以上開けた方が有意に透明治癒率が高かった．

　4．donorの年齢と透明治癒率との間には，有意な相関は認められなかった．

Out of a consecutive series of 312 eyes that underwent penetrating keratoplasty during a 13 -year period through 1987, there were 20 patients in whom keratoplasty was performed later on the fellow eye. We evaluated the outcome in these 20 bilateral cases.

Postsurgical clear grafts accounted for 62.5% of the eyes. There was no statistically significance between the incidence of clear graft in the first eye(55%) and the second eye (70%).

When the second eye was operated in less than one year after surgery in the first eye, the graft remained clear in 44% of the eyes. When surgery was performed later than one year, the graft remained clear in 77.3% of the eyes. The difference was significant.

The incidence of clear graft was not dependent on the age of the donor, either for the first or the second operation.

Rinsho Ganka (Jpn J Clin Ophthalmol) 42(5) : 529-532, 1988